Offered for the first time in decades, this distinguished estate presents one of Bluffview's most treasured settings. With its timeless, understated allure, the 1940 Howard Meyer-designed residence rests on more than two acres of exceptional topography framed by majestic trees and mature landscaping. Beginning with its picturesque private drive, the property reflects a rare sense of scale, privacy, and architectural integrity. Spanning almost 9,400 sq ft with generous room proportions, high ceilings, and floor-to-ceiling picture windows, you'll be swept back to a time of gracious entertaining, treasured family gatherings, and a home filled with love, laughter, and adventure. The first level is anchored by a welcoming foyer and elegant formals showcasing sweeping views of the spectacular grounds. A light-filled sunroom with an arched ceiling and brick flooring offers a tranquil retreat. Overlooking the lawn, the charming central library appointed with basketweave-patterned hardwoods, a full bath, and one of four fireplaces leads to an expansive Saltillo-tiled great room. A whimsically hand-painted kitchen and breakfast room capture the warmth and charm of this enchanting home, while intricate moldings, double staircases, silver closets, generous storage, and an elevator accessible from three sides add to its thoughtful design. Upstairs, the primary suite offers a spacious sitting room and two full baths, each with generous closets and dressing areas. Five additional bedrooms (or four + a game room) and three full baths complete the second level. A collection of detached spaces enhances the property's versatility, including a two-room guesthouse, a cabana or fitness studio, and separate pool baths. The breathtaking grounds of 5007 Seneca are nearly indescribable. Enveloped in lush, manicured landscaping, brick pathways meander through multiple patios and a impressive brick-bordered parterre garden while expansive green lawns encircle this extraordinary setting.